Activity in Thalassemia
- Many patients with thalassemia intermedia should be able to tolerate most daily activities. However, once the anemia worsens, exercise intolerance develops and may represent a warning sign indicating the need for initiation of blood transfusions.
- Massive splenomegaly has been observed in severe cases and is a cause for limiting the patient's activity for fear of injury to the abdomen causing rupture of the spleen.
- Regular transfusions decrease the size of the spleen in most instances, allowing splenectomy to be avoided whenever possible.
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